ng_attempts; $rval = $this->contact_service( 'ping', array( 'args' => $vaultpress_pings ) ); if ( $rval || $ping_attempts >= 3 ) break; if ( !$rval ) usleep(500000); } while ( true ); if ( !$rval ) { if ( $this->get_option( 'connection_error_code' ) !== -8 ) { // Do not save pings when the subscription is inactive. $__vp_recursive_ping_lock = true; $this->ai_ping_insert( serialize( $vaultpress_pings ) ); } } $this->reset_pings(); if ( $close_wpdb ) { $wpdb->__destruct(); unset( $wpdb ); } return $rval; } function resolve_content_dir() { // Take the easy way out if ( defined( 'WP_CONTENT_DIR' ) ) { if ( substr( WP_CONTENT_DIR, -1 ) != DIRECTORY_SEPARATOR ) return WP_CONTENT_DIR . DIRECTORY_SEPARATOR; return WP_CONTENT_DIR; } // Best guess if ( defined( 'ABSPATH' ) ) { if ( substr( ABSPATH, -1 ) != DIRECTORY_SEPARATOR ) return ABSPATH . DIRECTORY_SEPARATOR . 'wp-content' . DIRECTORY_SEPARATOR; return ABSPATH . 'wp-content' . DIRECTORY_SEPARATOR; } // Run with a solid assumption: WP_CONTENT_DIR/vaultpress/vaultpress.php return dirname( __DIR__ ) . DIRECTORY_SEPARATOR; } function resolve_upload_path() { $upload_path = false; $upload_dir = wp_upload_dir(); if ( isset( $upload_dir['basedir'] ) ) $upload_path = $upload_dir['basedir']; // Nothing recorded? use a best guess! if ( !$upload_path || $upload_path == realpath( ABSPATH ) ) return $this->resolve_content_dir() . 'uploads' . DIRECTORY_SEPARATOR; if ( substr( $upload_path, -1 ) != DIRECTORY_SEPARATOR ) $upload_path .= DIRECTORY_SEPARATOR; return $upload_path; } function load_first( $value ) { $value = array_unique( $value ); // just in case there are duplicates return array_merge( preg_grep( '/vaultpress\.php$/', $value ), preg_grep( '/vaultpress\.php$/', $value, PREG_GREP_INVERT ) ); } function is_multisite() { if ( function_exists( 'is_multisite' ) ) return is_multisite(); return false; } function is_main_site() { if ( !function_exists( 'is_main_site' ) || !$this->is_multisite() ) return true; return is_main_site(); } function is_registered() { $key = $this->get_option( 'key' ); $secret = $this->get_option( 'secret' ); return !empty( $key ) && !empty( $secret ); } function clear_connection() { $this->delete_option( 'connection' ); $this->delete_option( 'connection_error_code' ); $this->delete_option( 'connection_error_message' ); $this->delete_option( 'connection_test' ); } function site_url() { $site_url = ''; // compatibility for WordPress MU Domain Mapping plugin if ( defined( 'DOMAIN_MAPPING' ) && DOMAIN_MAPPING && ! function_exists( 'domain_mapping_siteurl' ) ) { if ( !function_exists( 'is_plugin_active' ) ) require_once ABSPATH . '/wp-admin/includes/plugin.php'; $plugin = 'wordpress-mu-domain-mapping/domain_mapping.php'; if ( is_plugin_active( $plugin ) ) include_once( WP_PLUGIN_DIR . '/' . $plugin ); } if ( function_exists( 'domain_mapping_siteurl' ) ) $site_url = domain_mapping_siteurl( false ); if ( empty( $site_url ) ) $site_url = site_url(); return $site_url; } /** * Sync the VaultPress options to WordPress.com if the Jetpack plugin is active. */ function sync_jetpack_options() { if ( class_exists( 'Jetpack_Sync' ) && method_exists( 'Jetpack_Sync', 'sync_options' ) && defined( 'JETPACK__VERSION' ) && version_compare( JETPACK__VERSION, '4.1', '<' ) ) { Jetpack_Sync::sync_options( __FILE__, $this->auto_register_option, $this->option_name ); } } /** * Add the VaultPress options to the Jetpack options management whitelist. * Allows Jetpack to register VaultPress options automatically. * * @param array $options The list of whitelisted option names. * * @return array The updated whitelist */ function add_to_jetpack_options_whitelist( $options ) { $options[] = $this->option_name; $options[] = $this->auto_register_option; return $options; } /** * When the VaultPress auto-register option is updated, run the registration call. * * This should only be run when the option is updated from the Jetpack/WP.com * API call, and only if the new key is different than the old key. * * @param mixed $old_value The old option value, or the option name (if add_option). * @param mixed $value The new option value. */ function updated_auto_register_option( $old_value, $value ) { // Not an API call or CLI call if ( ! class_exists( 'WPCOM_JSON_API_Update_Option_Endpoint' ) && ! ( defined( 'WP_CLI' ) && WP_CLI ) ) { return; } remove_action( "update_option_{$this->auto_register_option}", array( $this, 'updated_auto_register_option' ) ); $defaults = array( 'key' => false, 'action' => 'register', // or `response` 'status' => 'working', 'error' => false, ); // `wp_parse_args` uses arrays, might as well be explicit about it. $registration = (array) json_decode( $value ); $registration = wp_parse_args( $registration, $defaults ); // If we have a working connection, don't update the key. if ( $this->check_connection( true ) ) { $registration['action'] = 'response'; $registration['error'] = 'VaultPress is already registered on this site.'; update_option( $this->auto_register_option, json_encode( $registration ) ); return; } if ( ! $registration['key'] ) { return; } $registration['action'] = 'response'; $response = $this->register( $registration['key'] ); if ( is_wp_error( $response ) ) { $registration['status'] = 'broken'; $registration['error'] = $response->get_error_message(); } else if ( $this->get_option( 'connection_error_code' ) ) { $registration['status'] = 'broken'; $registration['error'] = $this->get_option( 'connection_error_message' ); } else { $registration['error'] = false; } update_option( $this->auto_register_option, json_encode( $registration ) ); } function add_global_actions_and_filters() { add_action( 'init', array( $this, 'sync_jetpack_options' ), 0, 99 ); add_filter( 'jetpack_options_whitelist', array( $this, 'add_to_jetpack_options_whitelist' ) ); add_action( "update_option_{$this->auto_register_option}", array( $this, 'updated_auto_register_option' ), 10, 2 ); add_action( "add_option_{$this->auto_register_option}", array( $this, 'updated_auto_register_option' ), 10, 2 ); add_action( 'admin_enqueue_scripts', array( $this, 'styles' ) ); } function add_admin_actions_and_filters() { add_action( 'admin_init', array( $this, 'admin_init' ) ); add_action( 'admin_menu', array( $this, 'admin_menu' ), 5 ); # Priority 5, so it's called before Jetpack's admin_menu. add_action( 'admin_head', array( $this, 'admin_head' ) ); } function add_listener_actions_and_filters() { add_action( 'admin_bar_menu', array( $this, 'toolbar' ), 999 ); // Comments add_action( 'delete_comment', array( $this, 'comment_action_handler' ) ); add_action( 'wp_set_comment_status', array( $this, 'comment_action_handler' ) ); add_action( 'trashed_comment', array( $this, 'comment_action_handler' ) ); add_action( 'untrashed_comment', array( $this, 'comment_action_handler' ) ); add_action( 'wp_insert_comment', array( $this, 'comment_action_handler' ) ); add_action( 'comment_post', array( $this, 'comment_action_handler' ) ); add_action( 'edit_comment', array( $this, 'comment_action_handler' ) ); // Commentmeta add_action( 'added_comment_meta', array( $this, 'commentmeta_insert_handler' ), 10, 2 ); add_action( 'updated_comment_meta', array( $this, 'commentmeta_modification_handler' ), 10, 4 ); add_action( 'deleted_comment_meta', array( $this, 'commentmeta_modification_handler' ), 10, 4 ); // Users if ( $this->is_main_site() ) { add_action( 'user_register', array( $this, 'userid_action_handler' ) ); add_action( 'password_reset', array( $this, 'userid_action_handler' ) ); add_action( 'profile_update', array( $this, 'userid_action_handler' ) ); add_action( 'user_register', array( $this, 'userid_action_handler' ) ); add_action( 'deleted_user', array( $this, 'userid_action_handler' ) ); } // Usermeta if ( $this->is_main_site() ) { // Keeping these action hooks for backward compatibility add_action( 'added_usermeta', array( $this, 'usermeta_action_handler' ), 10, 4 ); add_action( 'update_usermeta', array( $this, 'usermeta_action_handler' ), 10, 4 ); add_action( 'delete_usermeta', array( $this, 'usermeta_action_handler' ), 10, 4 ); add_action( 'added_user_meta', array( $this, 'usermeta_action_handler' ), 10, 4 ); add_action( 'update_user_meta', array( $this, 'usermeta_action_handler' ), 10, 4 ); add_action( 'delete_user_meta', array( $this, 'usermeta_action_handler' ), 10, 4 ); } // Posts add_action( 'delete_post', array( $this, 'post_action_handler' ) ); add_action( 'trash_post', array( $this, 'post_action_handler' ) ); add_action( 'untrash_post', array( $this, 'post_action_handler' ) ); add_action( 'edit_post', array( $this, 'post_action_handler' ) ); add_action( 'save_post', array( $this, 'post_action_handler' ) ); add_action( 'wp_insert_post', array( $this, 'post_action_handler' ) ); add_action( 'edit_attachment', array( $this, 'post_action_handler' ) ); add_action( 'add_attachment', array( $this, 'post_action_handler' ) ); add_action( 'delete_attachment', array( $this, 'post_action_handler' ) ); add_action( 'private_to_publish', array( $this, 'post_action_handler' ) ); add_action( 'wp_restore_post_revision', array( $this, 'post_action_handler' ) ); // Postmeta add_action( 'added_post_meta', array( $this, 'postmeta_insert_handler' ), 10, 4 ); add_action( 'update_post_meta', array( $this, 'postmeta_modification_handler' ), 10, 4 ); add_action( 'updated_post_meta', array( $this, 'postmeta_modification_handler' ), 10, 4 ); add_action( 'delete_post_meta', array( $this, 'postmeta_modification_handler' ), 10, 4 ); add_action( 'deleted_post_meta', array( $this, 'postmeta_modification_handler' ), 10, 4 ); add_action( 'added_postmeta', array( $this, 'postmeta_action_handler' ), 10, 3 ); add_action( 'update_postmeta', array( $this, 'postmeta_action_handler' ), 10, 3 ); add_action( 'delete_postmeta', array( $this, 'postmeta_action_handler' ), 10, 3 ); // Links add_action( 'edit_link', array( $this, 'link_action_handler' ) ); add_action( 'add_link', array( $this, 'link_action_handler' ) ); add_action( 'delete_link', array( $this, 'link_action_handler' ) ); // Taxonomy add_action( 'created_term', array( $this, 'term_handler' ), 2 ); add_action( 'edited_terms', array( $this, 'term_handler' ), 2 ); add_action( 'delete_term', array( $this, 'term_handler' ), 2 ); add_action( 'edit_term_taxonomy', array( $this, 'term_taxonomy_handler' ) ); add_action( 'delete_term_taxonomy', array( $this, 'term_taxonomy_handler' ) ); add_action( 'edit_term_taxonomies', array( $this, 'term_taxonomies_handler' ) ); add_action( 'add_term_relationship', array( $this, 'term_relationship_handler' ), 10, 2 ); add_action( 'delete_term_relationships', array( $this, 'term_relationships_handler' ), 10, 2 ); add_action( 'set_object_terms', array( $this, 'set_object_terms_handler' ), 10, 3 ); // Files if ( $this->is_main_site() ) { add_action( 'switch_theme', array( $this, 'theme_action_handler' ) ); add_action( 'activate_plugin', array( $this, 'plugin_action_handler' ) ); add_action( 'deactivate_plugin', array( $this, 'plugin_action_handler' ) ); } add_action( 'wp_handle_upload', array( $this, 'upload_handler' ) ); // Options add_action( 'deleted_option', array( $this, 'option_handler' ), 1 ); add_action( 'updated_option', array( $this, 'option_handler' ), 1 ); add_action( 'added_option', array( $this, 'option_handler' ), 1 ); $this->add_woocommerce_actions(); $this->add_vp_required_filters(); } function add_woocommerce_actions() { add_action( 'woocommerce_tax_rate_deleted', array( $this, 'woocommerce_tax_rate_handler' ), 10, 1 ); add_action( 'woocommerce_tax_rate_updated', array( $this, 'woocommerce_tax_rate_handler' ), 10, 1 ); add_action( 'woocommerce_tax_rate_added', array( $this, 'woocommerce_tax_rate_handler' ), 10, 1 ); add_action( 'woocommerce_new_order_item', array( $this, 'woocommerce_order_item_handler' ), 10, 1 ); add_action( 'woocommerce_update_order_item', array( $this, 'woocommerce_order_item_handler' ), 10, 1 ); add_action( 'woocommerce_delete_order_item', array( $this, 'woocommerce_order_item_handler' ), 10, 1 ); add_action( 'added_order_item_meta', array( $this, 'woocommerce_order_item_meta_handler' ), 10, 1 ); add_action( 'updated_order_item_meta', array( $this, 'woocommerce_order_item_meta_handler' ), 10, 1 ); add_action( 'deleted_order_item_meta', array( $this, 'woocommerce_order_item_meta_handler' ), 10, 1 ); add_action( 'woocommerce_attribute_added', array( $this, 'woocommerce_attribute_handler' ), 10, 1 ); add_action( 'woocommerce_attribute_updated', array( $this, 'woocommerce_attribute_handler' ), 10, 1 ); add_action( 'woocommerce_attribute_deleted', array( $this, 'woocommerce_attribute_handler' ), 10, 1 ); } function add_vp_required_filters() { // Log ins if ( $this->get_option( 'login_lockdown' ) ) { add_action( 'login_form', array( $this, 'add_js_token' ) ); add_filter( 'authenticate', array( $this, 'authenticate' ), 999 ); } // Report back to VaultPress add_action( 'shutdown', array( $this, 'do_pings' ) ); // VaultPress likes being first in line add_filter( 'pre_update_option_active_plugins', array( $this, 'load_first' ) ); } function get_jetpack_email() { if ( ! class_exists( 'Jetpack' ) ) { return false; } // For version of Jetpack prior to 7.7. if ( defined( 'JETPACK__VERSION' ) && version_compare( JETPACK__VERSION, '7.7', '<' ) && ! class_exists( 'Jetpack_IXR_Client' ) ) { Jetpack::load_xml_rpc_client(); } $xml = new Jetpack_IXR_Client( array( 'user_id' => get_current_user_id() ) ); $xml->query( 'wpcom.getUserEmail' ); if ( ! $xml->isError() ) { return $xml->getResponse(); } return new WP_Error( $xml->getErrorCode(), $xml->getErrorMessage() ); } function get_key_via_jetpack( $already_purchased = false ) { if ( ! class_exists( 'Jetpack' ) ) { return false; } // For version of Jetpack prior to 7.7. if ( defined( 'JETPACK__VERSION' ) && version_compare( JETPACK__VERSION, '7.7', '<' ) && ! class_exists( 'Jetpack_IXR_Client' ) ) { Jetpack::load_xml_rpc_client(); } $xml = new Jetpack_IXR_Client( array( 'user_id' => Jetpack_Options::get_option( 'master_user' ) ) ); $xml->query( 'vaultpress.registerSite', $already_purchased ); if ( ! $xml->isError() ) { return $xml->getResponse(); } return new WP_Error( $xml->getErrorCode(), $xml->getErrorMessage() ); } function register_via_jetpack( $already_purchased = false ) { $registration_key = $this->get_key_via_jetpack( $already_purchased ); if ( is_wp_error( $registration_key ) ) { return $registration_key; } return self::register( $registration_key ); } } $vaultpress = VaultPress::init(); if ( isset( $_GET['vaultpress'] ) && $_GET['vaultpress'] ) { if ( !function_exists( 'wp_magic_quotes' ) ) { // Escape with wpdb. $_GET = add_magic_quotes( $_GET ); $_POST = add_magic_quotes( $_POST ); $_COOKIE = add_magic_quotes( $_COOKIE ); $_SERVER = add_magic_quotes( $_SERVER ); // Force REQUEST to be GET + POST. If SERVER, COOKIE, or ENV are needed, use those superglobals directly. $_REQUEST = array_merge( $_GET, $_POST ); } else { wp_magic_quotes(); } if ( !function_exists( 'wp_get_current_user' ) ) include ABSPATH . '/wp-includes/pluggable.php'; // TODO: this prevents some error notices but do we need it? is there a better way to check capabilities/logged in user/etc? if ( function_exists( 'wp_cookie_constants' ) && !defined( 'AUTH_COOKIE' ) ) wp_cookie_constants(); $vaultpress->parse_request( null ); die(); } // only load hotfixes if it's not a VP request require_once __DIR__ . '/class.vaultpress-hotfixes.php'; $hotfixes = new VaultPress_Hotfixes(); // Add a helper method to WP CLI for auto-registerion via Jetpack if ( defined( 'WP_CLI' ) && WP_CLI ) { require_once __DIR__ . '/class.vaultpress-cli.php'; } require_once __DIR__ . '/cron-tasks.php'; Oxford-AstraZeneca's Covishield vaccine cleared by expert panel - Social News XYZ
Social News XYZ     

Oxford-AstraZeneca’s Covishield vaccine cleared by expert panel

Oxford-AstraZeneca's Covishield vaccine cleared by expert panel

New Delhi, Jan 1 (SocialNews.XYZ) In a step closer towards India approving its first coronavirus vaccine, the Subject Expert Committee of the Central Drug Standard Control Organisation on Friday recommended emergency use of Oxford-AstraZeneca's 'Covishield' vaccine.

The application will be sent to Drugs Controller General of India (DCGI) V.G. Somani for final approval.

 

The expert panel had convened a meeting on Friday afternoon to take a call on the emergency use authorisation sought by the Serum Institute of India, which is Covishield's manufacturer, and Bharat Biotech for their coronavirus vaccine candidates.

A decision on Bharat Biotech's Covaxin was still awaited at the meeting which is still underway, the Health Ministry said.

The Pune-based Serum Institute has partnered with Oxford-AstraZeneca for conducting clinical trials and manufacturing 'Covishield' while Bharat Biotech has collaborated with the Indian Council of Medical Research (ICMR) to make 'Covaxin'.

America's Pfizer was the first one to apply for the accelerated approval on December 4, followed by Serum and Bharat Biotech on December 6 and 7, respectively. Pfizer has, however, sought more time to present the data.

As India awaits for a silver bullet against coronavirus with bated breath, the DCGI, on Thursday, hinted at the approval of vaccine and said that the country will have a "Happy New Year with something in hand".

The meeting comes a day before dry-run of the vaccine is slated to commence in all the states and Union Territories to equip the administration in management of vaccine supply, storage and logistics, including cold chain management.

The Central government plans to vaccinate nearly 30 crore people in the first phase of the drive. It will be offered to one crore healthcare workers, along with 2 crore frontline and essential workers and 27 crore elderly, mostly above the age of 50 years with co-morbidities.

Source: IANS

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Oxford-AstraZeneca's Covishield vaccine cleared by expert panel

About Gopi

Gopi Adusumilli is a Programmer. He is the editor of SocialNews.XYZ and President of AGK Fire Inc.

He enjoys designing websites, developing mobile applications and publishing news articles on current events from various authenticated news sources.

When it comes to writing he likes to write about current world politics and Indian Movies. His future plans include developing SocialNews.XYZ into a News website that has no bias or judgment towards any.

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