Mario Balotelli's early double in the fourth and 28th minutes seemingly put Nice in charge on Thursday, but Manuel Fernandes' penalty at the stroke of half-time turned the tide, reports Tass news agency.
Lokomotiv managed to recover with a hat trick scored by Fernandes (in the 45th, 69th and 77th minutes).
The second leg will be held at Moscow's RZD-Arena on February 22.
(This story has not been edited by Social News XYZ staff and is auto-generated from a syndicated feed.)
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